SLF80821178 hydrochloride
Product Specifications
CAS Number
2764877-62-3
Target
LPL Receptor
Related Pathways
GPCR/G Protein
Bioactivity
SLF80821178 hydrochloride is an orally active anticancer compound that effectively targets the inhibitory function of Spns2 (sphingosine-1-phosphate transporter) and can significantly reduce the release of sphingosine-1-phosphate (S1P) in HeLa cells. Has an IC50 value of 51 nM. Furthermore, SLF80821178 hydrochloride effectively reduced circulating lymphocyte levels in a mouse model without significant effects on plasma S1P levels.
Smiles
Cl.O=C(NC1=CC=C(C=C1)CCCCCCCCCC)N2CCNCC2
Molecular Formula
C21H36ClN3O
Molecular Weight
381.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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