CCR1 antagonist 12
Product Specifications
CAS Number
921208-19-7
Target
CCR
Related Pathways
Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology
Bioactivity
CCR1 antagonist12 (Compound 12) is an antagonist of CCR1, exhibiting an IC50 of 3 nM against human CCR1. It inhibits the chemotaxis through pores induced by CCL3, with an IC50 of 0.009 μM. Additionally, CCR1 antagonist12 demonstrates favorable pharmacokinetic properties in a rat model.
Smiles
O=C(C=CC1=CC(OC)=C(Cl)C=C1NC(=O)C)N2CC3N(CC4=CC=C(F)C=C4)C(COC3)C2
Molecular Formula
C25H27ClFN3O4
Molecular Weight
487.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10319759 96 Well
Bovine Cytochrome b5 domain containing protein 1 (CYB5D1) ELISA Kit
Sign In for Pricing
View Details 
MBS2004078-01 0.1 mL
Biotin-Linked Antibody to B-Cell Activating Factor (BAFF)
Sign In for Pricing
View Details MBS2004078-02 0.2 mL
Biotin-Linked Antibody to B-Cell Activating Factor (BAFF)
Sign In for Pricing
View Details 
MBS2004078-03 0.5 mL
Biotin-Linked Antibody to B-Cell Activating Factor (BAFF)
Sign In for Pricing
View Details MBS2004078-04 1 mL
Biotin-Linked Antibody to B-Cell Activating Factor (BAFF)
Sign In for Pricing
View Details MBS2004078-05 5 mL
Biotin-Linked Antibody to B-Cell Activating Factor (BAFF)
Sign In for Pricing
View Details