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LXQ46

Product Specifications

CAS Number

2097148-94-0

Target

Phosphatase

Related Pathways

Metabolism

Bioactivity

LXQ46 is an orally effective inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 0.190 ?M. It enhances insulin and leptin signaling pathways in insulin-resistant C2C12 cells. Additionally, LXQ46 improves type 2 diabetes and increases insulin tolerance in mouse models.

Smiles

BrC=1C(Br)=C(C=C(O)C1O)C2=NC=C(O2)C=3C=CC(OC4=CC=C(OCC)C=C4)=CC3

Molecular Formula

C23H17Br2NO5

Molecular Weight

547.19

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/222088474998603870/T88568

Available Sizes

Curated Selection

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