LXQ46
Product Specifications
CAS Number
2097148-94-0
Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
LXQ46 is an orally effective inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 0.190 ?M. It enhances insulin and leptin signaling pathways in insulin-resistant C2C12 cells. Additionally, LXQ46 improves type 2 diabetes and increases insulin tolerance in mouse models.
Smiles
BrC=1C(Br)=C(C=C(O)C1O)C2=NC=C(O2)C=3C=CC(OC4=CC=C(OCC)C=C4)=CC3
Molecular Formula
C23H17Br2NO5
Molecular Weight
547.19
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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