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ZM-306416 hydrochloride

Product Specifications

CAS Number

196603-47-1

Target

VEGFR|||EGFR

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Bioactivity

ZM-306416 (CB 676475) hydrochloride is a potent inhibitor of VEGFR, demonstrating IC50 values of 0.1 µM for KDR and 2 µM for Flt. Additionally, this compound acts as an inhibitor of EGFR with an IC50 value of less than 10 nM.

Smiles

Cl.FC1=CC(Cl)=CC=C1NC=2N=CN=C3C=C(OC)C(OC)=CC32

Molecular Formula

C16H14Cl2FN3O2

Molecular Weight

370.21

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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