NH2-PEG3-VC-PAB-MMAE
Product Specifications
CAS Number
2641442-97-7
Target
Drug-Linker Conjugates for ADC, Microtubule Associated
Related Pathways
Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling
Bioactivity
NH2-PEG3-VC-PAB-MMAE is a drug-linker conjugate for ADC, which combines a cleavable ADC linker (NH2-PEG3-VC-PAB) with a potent tubulin inhibitor Monomethylauristatin E (MMAE) . It is mainly used in the synthesis of antibody-drug conjugates (ADCs) .
Smiles
[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(COCCOCCOCCN)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Molecular Formula
C66H109N11O16
Molecular Weight
1312.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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