MYX1715
Product Specifications
CAS Number
2445448-66-6
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
MYX1715 is an inhibitor of N-myristoyltransferase (NMT), exhibiting a KD of 0.09 nM. It inhibits the proliferation of LU0884 and LU2511, with IC50 values of 44 nM and 9 nM, respectively. In mouse models, MYX1715 demonstrates antitumor activity against neuroblastoma and gastric cancer. Additionally, MYX1715 can be utilized as a toxin in ADCs.
Smiles
O=C(C1=NN(C(=C1CCOC=2C=C(Cl)C=CC2C=3C=CC4=NC=C(N4C3)CCN)C)C)N(C)C
Molecular Formula
C25H29ClN6O2
Molecular Weight
480.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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