KSI-6666
Product Specifications
CAS Number
1807873-14-8
Target
LPL Receptor
Related Pathways
GPCR/G Protein
Bioactivity
KSI-6666 is an orally effective competitive antagonist of sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 value of 6.4 nM. It exhibits anti-inflammatory activity in models of autoimmune encephalomyelitis and T-cell transfer-induced colitis.
Smiles
O=C(O)C1CN(CC2=CC(=CC=C2C)C(N(C3=CC=C(Cl)C(=C3)C(F)(F)F)CC)C)C1
Molecular Formula
C23H26ClF3N2O2
Molecular Weight
454.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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