PRMT5-IN-41

3034034-32-4

Histone Methyltransferase, Potassium Channel

Membrane transporter/Ion channel, Chromatin/Epigenetic

PRMT5-IN-41 (compound 130) is an effective orally active inhibitor of PRMT5. It inhibits the hERG ion channel with an IC50 of 1.36 μM.

C(N(C)[C@H]1C=2C(OC1)=CC(C(C(F)(F)F)(F)F)=CC2)(=O)C=3C=C4N5C(C(N)=NC4=CC3)=CN=C5

C22H16F5N5O2

477.39

Ice Packs

-20°C