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Philanthotoxin 74 diTFA

Product Specifications

CAS Number

401601-12-5

Target

IGluR

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Bioactivity

Philanthotoxin 74 (PhTx 74) diTFA acts as an antagonist to AMPAR, specifically inhibiting GluR3 and GluR1 with IC50 values of 263 nM and 296 nM, respectively.

Smiles

OC(C(F)(F)F)=O.OC(C=C1)=CC=C1C[C@H](NC(CCC)=O)C(NCCCCCCCNCCCCN)=O.OC(C(F)(F)F)=O

Molecular Formula

C28H44F6N4O7

Molecular Weight

662.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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