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VU6008677

Product Specifications

CAS Number

2170550-99-7

Target

AChR, Cytochromes P450

Related Pathways

Neuroscience, Metabolism

Bioactivity

VU6008677 is a positive allosteric modulator (PAM) of M4 with an EC50 of 120 nM for hM4. It inhibits cytochrome P450 (cytochrome P450) and exhibits a high microsomal clearance rate and high plasma protein binding in rats.

Smiles

ClC1=C(N=C2OC=3C(=NC=NC3C2=C1C)NC4CC4)C

Molecular Formula

C14H13ClN4O

Molecular Weight

288.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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