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HC-258

Product Specifications

CAS Number

3056128-12-9

Target

YAP

Related Pathways

Stem Cells

Bioactivity

HC-258 is a direct TEAD inhibitor that forms a covalent bond with Cys380, a cysteine residue of TEAD proteins, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 in MDA-MB-231 cells.

Smiles

O=C(C=C)NC1=CC=CC(=C1)NC=2C=CC=C(OCCCCC)C2

Molecular Formula

C20H24N2O2

Molecular Weight

324.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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