F594-1001
Product Specifications
CAS Number
1215326-44-5
Target
SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
F594-1001 (compound 6) serves as a potent, highly selective inhibitor of SARS-CoV-2 Mac1-ADP-ribose, displaying IC 50 values of 8.5 ?M, 68 ?M, and 45 ?M in AS, FP, and FRET assays, respectively. It binds directly to SARS-CoV-2 Mac1 and demonstrates dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity.
Smiles
O=C(C=1C=C(OC)C=C(OC)C1)N(CC=2C=CC=C(Cl)C2)CCC(=O)N3CCNCC3
Molecular Formula
C23H28ClN3O4
Molecular Weight
445.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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