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F594-1001

Product Specifications

CAS Number

1215326-44-5

Target

SARS-CoV

Related Pathways

Microbiology/Virology

Bioactivity

F594-1001 (compound 6) serves as a potent, highly selective inhibitor of SARS-CoV-2 Mac1-ADP-ribose, displaying IC 50 values of 8.5 ?M, 68 ?M, and 45 ?M in AS, FP, and FRET assays, respectively. It binds directly to SARS-CoV-2 Mac1 and demonstrates dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity.

Smiles

O=C(C=1C=C(OC)C=C(OC)C1)N(CC=2C=CC=C(Cl)C2)CCC(=O)N3CCNCC3

Molecular Formula

C23H28ClN3O4

Molecular Weight

445.94

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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