HU 433
Product Specifications
CAS Number
1220887-84-2
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein
Bioactivity
HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNγ-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.
Smiles
O(C)C1=C([C@H]2[C@@]3(C(C)(C)[C@@](C3)(C(CO)=C2)[H])[H])C(OC)=CC(C(CCCCCC)(C)C)=C1
Molecular Formula
C27H42O3
Molecular Weight
414.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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