Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

KT-333

Product Specifications

CAS Number

2502186-79-8

Target

STAT, Molecular Glues

Related Pathways

JAK/STAT signaling, Stem Cells, PROTAC

Purity

0.9812

Bioactivity

KT-333 is a potent, highly selective, heterobifunctional small molecule degrader of STAT3 for the treatment of a variety of STAT3-dependent pathologies, including hematologic malignancies and solid tumors.KT-333 specifically binds to STAT3 proteins at one end of the spectrum, and binds to the E3 ubiquitin ligase, VHL, at the other end.

Smiles

C(N[C@H](COC1=C(Cl)C(CCCC(N[C@H](C(=O)N2[C@H](C(N[C@@H](C)C3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2)C(C)(C)C)=O)=CC=C1)CCC(N)=O)(=O)[C@H]5N6[C@](CC5)(CCN(C(C)=O)C[C@H](NC(=O)C7=CC=8C(N7)=CC=C(C(P(=O)(O)O)=O)C8)C6=O)[H]

Molecular Formula

C60H74ClN10O14PS

Molecular Weight

1257.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Multiplex Assay Kit for Leucine Rich Repeat Kinase 2 (LRRK2), etc. by FLIA (Flow Luminescence Immunoassay)
TRV-0031294 96 Tests

Multiplex Assay Kit for Leucine Rich Repeat Kinase 2 (LRRK2), etc. by FLIA (Flow Luminescence Immunoassay)

Sign In for Pricing
View Details
POLR2G Antibody
A31610-50UL 50 μL

POLR2G Antibody

Sign In for Pricing
View Details
Recombinant Mycobacterium leprae Anthranilate synthase component 1 (trpE), partial
MBS1453953 Inquire

Recombinant Mycobacterium leprae Anthranilate synthase component 1 (trpE), partial

Sign In for Pricing
View Details
Rgs13 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K4425202 1.0 µg DNA

Rgs13 sgRNA CRISPR Lentivector (Mouse) (Target 1)

Sign In for Pricing
View Details
BCNP1 CRISPR Activation Plasmid (m2)
sc-437173-ACT-2 20 µg

BCNP1 CRISPR Activation Plasmid (m2)

Sign In for Pricing
View Details
ZNF705D Human Over-expression Lysate
orb1363641 20 µg

ZNF705D Human Over-expression Lysate

Sign In for Pricing
View Details