NPD8790
Product Specifications
CAS Number
615281-26-0
Target
Parasite, Mitochondrial Metabolism
Related Pathways
Metabolism, Microbiology/Virology
Bioactivity
NPD8790 is a selective inhibitor of mitochondrial respiratory complex I, with an IC50 of 2.4 μM for the complex I in Caenorhabditis elegans. It demonstrates greater selectivity for nematode species mitochondria compared to those of humans, cattle, and mice. NPD8790 acts as an anthelmintic, effectively eliminating adult soil-transmitted worms.
Smiles
N=1C=2C=CC=CC2N(C1C(C3=CC=C(C=C3)CC(C)C)C)C
Molecular Formula
C20H24N2
Molecular Weight
292.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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