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PARP1-IN-20

Product Specifications

CAS Number

2659357-95-4

Target

PARP

Related Pathways

DNA Damage/DNA Repair|||Chromatin/Epigenetic

Bioactivity

PARP1-IN-20 (compound 19A10) serves as a highly effective inhibitor of PARP1, demonstrating an IC50 value of 4.62 nM, but exhibits a relatively minimal PARP-trapping effect when compared with Veliparib, where it shows an IC50 (MDA-MB-436) greater than 100 ?M.

Smiles

O=C(N)C=1C=CC=C2N=C(NC21)C=3C=CC(=CC3)C(=O)N4CCN(C(=O)C=5N=C(Br)SC5)CC4

Molecular Formula

C23H19BrN6O3S

Molecular Weight

539.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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