PARP1-IN-20
Product Specifications
CAS Number
2659357-95-4
Target
PARP
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
PARP1-IN-20 (compound 19A10) serves as a highly effective inhibitor of PARP1, demonstrating an IC50 value of 4.62 nM, but exhibits a relatively minimal PARP-trapping effect when compared with Veliparib, where it shows an IC50 (MDA-MB-436) greater than 100 ?M.
Smiles
O=C(N)C=1C=CC=C2N=C(NC21)C=3C=CC(=CC3)C(=O)N4CCN(C(=O)C=5N=C(Br)SC5)CC4
Molecular Formula
C23H19BrN6O3S
Molecular Weight
539.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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