PROTAC HPK1 Degrader-2
Product Specifications
CAS Number
2893885-31-7
Target
PROTACs, MAPK
Related Pathways
MAPK, PROTAC
Bioactivity
PROTACHPK1 Degrader-2 (compound 3) is a PROTAC degrader of HPK1, exhibiting a DC50 of 23 nM in human PBMCs. This compound plays a crucial role in cancer research.
Smiles
O=C1NC(=O)CCN1C2=CC=C(C=C2)N3CCN(C(=O)CCN4CC5=C(C=C(C=C5CC4)C6=NC7=C(N=C6)NC=C7C=8C=CC(C(=O)N(C)C)=C(C8)C)C)CC3
Molecular Formula
C43H47N9O4
Molecular Weight
753.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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