PROTAC HPK1 Degrader-2

Product Specifications

CAS Number

2893885-31-7

Target

PROTACs|||MAPK

Related Pathways

MAPK|||PROTAC

Bioactivity

PROTACHPK1 Degrader-2 (compound 3) is a PROTAC degrader of HPK1, exhibiting a DC50 of 23 nM in human PBMCs. This compound plays a crucial role in cancer research.

Smiles

O=C1NC(=O)CCN1C2=CC=C(C=C2)N3CCN(C(=O)CCN4CC5=C(C=C(C=C5CC4)C6=NC7=C(N=C6)NC=C7C=8C=CC(C(=O)N(C)C)=C(C8)C)C)CC3

Molecular Formula

C43H47N9O4

Molecular Weight

753.89

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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