JAK2-IN-10
Product Specifications
CAS Number
3035735-18-0
Target
JAK
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic, Stem Cells, Angiogenesis
Bioactivity
JAK2-IN-10 (compound 5) is a potent inhibitor of JAK2v617f, with an IC50 value of ≤10 nM.
Smiles
O=C1N(C2=C3C(=C(N=C3NC=C2N1C)C4=CN(CC)N=C4F)C=5C=C6C(=CC5)N(C([2H])([2H])[2H])N=C6)[C@H]7CC[C@](NC(=O)C8CC8)(C)CC7
Molecular Formula
C33H33D3FN9O2
Molecular Weight
612.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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