KIF18A-IN-10
Product Specifications
CAS Number
3034542-28-1
Target
Microtubule Associated, Kinesin
Related Pathways
Cytoskeletal Signaling
Bioactivity
KIF18A-IN-10 (Compound 24) is a potent inhibitor of KIF18A with an IC50 value of 3.8 nM. It exhibits anticancer activity with IC50 values below 100 nM in OVCAR3 and MDA-MB-157 cells.
Smiles
O=C(NC1=NC2=C(C=NN2C3CC(F)(F)C3)C=C1)C4=CC=C(C=C4N5CCC6(CC5)CC6)NS(=O)(=O)CCO
Molecular Formula
C26H30F2N6O4S
Molecular Weight
560.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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