BMS-737
Product Specifications
CAS Number
1356053-63-8
Target
Cytochromes P450
Related Pathways
Metabolism
Bioactivity
BMS-737 (compound 33), a non-steroidal, reversible small molecule inhibitor, demonstrates 11-fold selectivity for CYP17 lyase over CYP17 hydroxylase. This compound is engineered to target castration-resistant prostate cancer (CRPC) and effectively lowers testosterone levels, while maintaining stable orrodermal hormone and glucocorticoid levels.
Smiles
FC1=CC=C(C=C1)N2N=CC=3C2=NC=CC3C=4C=NC=NC4N
Molecular Formula
C16H11FN6
Molecular Weight
306.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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