CDK5-IN-4
Product Specifications
CAS Number
1212711-91-5
Target
GSK-3, CDK
Related Pathways
Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Stem Cells
Bioactivity
CDK5-IN-4 (compound 4), a potent type-II multikinase inhibitor, targets CDK5 with an IC 50 of 9.8 μM. Additionally, it inhibits GSK-3α, GSK-3β, CDK9, and CDK2, demonstrating IC 50 values of 0.98, 4.00, 1.76, and 6.24 μM, respectively. This compound is applicable in glioblastoma research.
Smiles
N([C@@H]1[C@@]2([C@@]([C@@H](NC(NCC3=CC=CC=C3)=O)CO2)(OC1)[H])[H])C=4N=C(C=CN4)C5=CC(F)=CC=C5
Molecular Formula
C24H24FN5O3
Molecular Weight
449.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GWB-A9AC3B 50 µg
HDAC-2, His-tag, Active Human Recombinant Protein, His Tag
Sign In for Pricing
View Details MKD75350-01 50 mg
5- (4-Carboxyphenyl) pyrimidine-2-carboxylic acid
Sign In for Pricing
View Details MKD75350-02 0.5 g
5- (4-Carboxyphenyl) pyrimidine-2-carboxylic acid
Sign In for Pricing
View Details