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CDK5-IN-4

Product Specifications

CAS Number

1212711-91-5

Target

GSK-3|||CDK

Related Pathways

Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Stem Cells

Bioactivity

CDK5-IN-4 (compound 4), a potent type-II multikinase inhibitor, targets CDK5 with an IC 50 of 9.8 ?M. Additionally, it inhibits GSK-3?, GSK-3?, CDK9, and CDK2, demonstrating IC 50 values of 0.98, 4.00, 1.76, and 6.24 ?M, respectively. This compound is applicable in glioblastoma research.

Smiles

N([C@@H]1[C@@]2([C@@]([C@@H](NC(NCC3=CC=CC=C3)=O)CO2)(OC1)[H])[H])C=4N=C(C=CN4)C5=CC(F)=CC=C5

Molecular Formula

C24H24FN5O3

Molecular Weight

449.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/217697283351773240/T88249

Available Sizes

Curated Selection

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