CDK5-IN-4
Product Specifications
CAS Number
1212711-91-5
Target
GSK-3|||CDK
Related Pathways
Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Stem Cells
Bioactivity
CDK5-IN-4 (compound 4), a potent type-II multikinase inhibitor, targets CDK5 with an IC 50 of 9.8 ?M. Additionally, it inhibits GSK-3?, GSK-3?, CDK9, and CDK2, demonstrating IC 50 values of 0.98, 4.00, 1.76, and 6.24 ?M, respectively. This compound is applicable in glioblastoma research.
Smiles
N([C@@H]1[C@@]2([C@@]([C@@H](NC(NCC3=CC=CC=C3)=O)CO2)(OC1)[H])[H])C=4N=C(C=CN4)C5=CC(F)=CC=C5
Molecular Formula
C24H24FN5O3
Molecular Weight
449.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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