CDK5-IN-4
Product Specifications
CAS Number
1212711-91-5
Target
GSK-3, CDK
Related Pathways
Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Stem Cells
Bioactivity
CDK5-IN-4 (compound 4), a potent type-II multikinase inhibitor, targets CDK5 with an IC 50 of 9.8 μM. Additionally, it inhibits GSK-3α, GSK-3β, CDK9, and CDK2, demonstrating IC 50 values of 0.98, 4.00, 1.76, and 6.24 μM, respectively. This compound is applicable in glioblastoma research.
Smiles
N([C@@H]1[C@@]2([C@@]([C@@H](NC(NCC3=CC=CC=C3)=O)CO2)(OC1)[H])[H])C=4N=C(C=CN4)C5=CC(F)=CC=C5
Molecular Formula
C24H24FN5O3
Molecular Weight
449.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1070977 Inquire
Recombinant Pectobacterium carotovorum subsp. carotovorum Membrane protein insertase YidC (yidC)
Sign In for Pricing
View Details