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3-sucCA

Product Specifications

CAS Number

94159-47-4

Target

Others|||Endogenous Metabolite|||Antibacterial

Related Pathways

Others|||Metabolism|||Microbiology/Virology

Bioactivity

3-SucCA (3-Succinylated cholic acid), a bile acid derived from microbial sources, primarily functions as a lumen-restricted metabolite. It plays a crucial role in mitigating the progression of MAFL-MASH in mouse models by altering the gut microbiota composition, notably by enhancing the proliferation of Akkermansia muciniphila. Notably, lower levels of 3-sucCA have been observed in patients with biopsy-proven MAFLD.

Smiles

O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](OC(CCC(O)=O)=O)CC4)[H])[H])[H])[H]

Molecular Formula

C28H44O8

Molecular Weight

508.64

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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