TK-642
Product Specifications
CAS Number
2765183-10-4
Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
TK-642 is a potent and selective SHP2 inhibitor with oral activity, based on pyrazole and pyrazine structures (IC50 = 2.7 nmol/L) . It effectively inhibits the proliferation of esophageal carcinoma cells and induces apoptosis, making it useful for studying esophageal cancer.
Smiles
ClC=1C=NC=CC1SC2=NNC=3N=C(C=NC23)N4CCC(C)(CN)CC4
Molecular Formula
C17H20ClN7S
Molecular Weight
389.91
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
032445-AP 200 µL
BCAS1, NT (BCAS1, AIBC1, NABC1, Breast carcinoma-amplified sequence 1, Amplified and overexpressed in breast cancer, Novel amplified in breast cancer 1) (AP) discontinued
Ask
View Details MBS2092451-01 0.1 mL
Biotin-Linked Polyclonal Antibody to A Disintegrin And Metalloprotease 10 (ADAM10)
Ask
View Details 
MBS2092451-02 0.2 mL
Biotin-Linked Polyclonal Antibody to A Disintegrin And Metalloprotease 10 (ADAM10)
Ask
View Details 
MBS2092451-03 0.5 mL
Biotin-Linked Polyclonal Antibody to A Disintegrin And Metalloprotease 10 (ADAM10)
Ask
View Details MBS2092451-04 1 mL
Biotin-Linked Polyclonal Antibody to A Disintegrin And Metalloprotease 10 (ADAM10)
Ask
View Details MBS2092451-05 5 mL
Biotin-Linked Polyclonal Antibody to A Disintegrin And Metalloprotease 10 (ADAM10)
Ask
View Details