Anticancer agent 216

2916406-02-3

Topoisomerase

DNA Damage/DNA Repair

Anticanceragent 216 (34A) is a camptothecin compound with IC50 values of 9.6 nM for MCF-7 cells and 11.6 nM for MDA-MB-231 cells.

[C@@H](C)(N)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC6=C(C5)OCO6

C23H21N3O6

435.43

Cool pack

-20°C