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Puxitatug samrotecan drug-linker

Product Specifications

CAS Number

3025787-81-6

Target

Drug-Linker Conjugates for ADC|||Topoisomerase

Related Pathways

Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

Bioactivity

Puxitatug samrotecan drug-linker (AZD8205 drug-linker), comprising a degradable ADC linker and the topoisomerase I inhibitor Exatecan, is utilized in the ADC (drug-linker conjugate for ADC) targeting the anti-B7-H4 antibody.

Smiles

O=C1N2C(C=3C(=C4C=5C(N3)=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(=O)C(SC[C@@H](C(O)=O)N)CC6=O)=O)=O)C(C)C)=O)C)=O)C5CCC4)C2)=CC7=C1COC(=O)[C@@]7(CC)O

Molecular Formula

C60H84N8O20S

Molecular Weight

1269.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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