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Fosmidomycin

Product Specifications

CAS Number

66508-53-0

Target

Antibiotic, Parasite

Related Pathways

Microbiology/Virology

Bioactivity

Fosmidomycin is an orally administered antibiotic that demonstrates antimalarial properties by inhibiting 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase. It effectively inhibits the P. falciparum strains 3D7, HB3, Dd2, and A2, with IC 50 values of 150, 71, 170, and 150 ng/mL, respectively. Fosmidomycin works synergistically with Clindamycin and alleviates malaria in a mouse model.

Smiles

O=CN(O)CCCP(=O)(O)O

Molecular Formula

C4H10NO5P

Molecular Weight

183.1

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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