Fosmidomycin
Product Specifications
CAS Number
66508-53-0
Target
Antibiotic, Parasite
Related Pathways
Microbiology/Virology
Bioactivity
Fosmidomycin is an orally administered antibiotic that demonstrates antimalarial properties by inhibiting 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase. It effectively inhibits the P. falciparum strains 3D7, HB3, Dd2, and A2, with IC 50 values of 150, 71, 170, and 150 ng/mL, respectively. Fosmidomycin works synergistically with Clindamycin and alleviates malaria in a mouse model.
Smiles
O=CN(O)CCCP(=O)(O)O
Molecular Formula
C4H10NO5P
Molecular Weight
183.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
