Anticancer agent 215

2916404-93-6

Topoisomerase

DNA Damage/DNA Repair

Anticanceragent 215 (1) is a camptothecin derivative with IC50 values of 5.2 nM and 8.2 nM against MCF-7 and MDA-MB-231 cells, respectively.

[C@H](C)(N)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(C)=C(F)C5

C23H22FN3O4

423.44

Ice Packs

-20°C