Lurosetron
Product Specifications
CAS Number
128486-54-4
Target
5-HT Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
Lurosetron (GR-87442) is the 6-fluoro analogue of Alosetron. It functions as a serotonin 5-HT3 receptor antagonist. Lurosetron inhibits recombinant (rbt) CYP1A2 with an IC50 of 0.1 μM and also inhibits other CYP subtypes, including rbtCYP2C9 and rbtCYP3A4, with IC50 values ranging from 3.5 μM to 16 μM.
Smiles
O=C1C=2C=3C=CC=C(F)C3N(C2CCN1CC=4NC=NC4C)C
Molecular Formula
C17H17FN4O
Molecular Weight
312.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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