EF-4-177
Product Specifications
CAS Number
2891574-93-7
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
EF-4-177, an orally active, allosteric CDK2 inhibitor, exhibits an IC50 value of 87 nM. It has been shown to disrupt spermatogenesis.
Smiles
[H+].N#CC=1C=CC2=C(C1)NC=C2CCNC3=CC=[C-](C=C3C(=O)[O-])[S+6]([F-])([F-])([F-])([F-])[F-]
Molecular Formula
C18H14F5N3O2S
Molecular Weight
431.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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