AD16
Product Specifications
CAS Number
311315-04-5
Target
Endonuclease
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
AD16 (Acetamide) acts as an inhibitor of LINE-1 retrotransposon endonuclease, exhibiting an IC50 value of 4.7 μM. It decreases LINE-1 retrotransposition in senescent cells and mitigates the resulting DNA damage and inflammation.
Smiles
O=C(NC1=CC=C2OC(=NC2=C1)C3=CC=C(C=C3)CC(=O)CSC4=NN=C5N4N=CN5N)CSC6=NN=C7N6N=CN7N
Molecular Formula
C24H20N14O3S2
Molecular Weight
616.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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