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CBu-Cit-PROTAC BRD4 Degrader-5

Product Specifications

CAS Number

2417369-73-2

Target

PROTAC-Linker Conjugates for PAC

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

CBu-Cit-PROTAC BRD4 Degrader-5, a cBu-Cit conjugated PROTAC degrader, effectively degrades BRD4 in both HER2 positive and negative breast cancer cell lines.

Smiles

CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](OCNC(OCC7=CC=C(NC([C@@H](NC(=O)C8(C(NCCCCCN9C(=O)C=CC9=O)=O)CCC8)CCCNC(N)=O)=O)C=C7)=O)C4)[C@@](C)(C)C)=O)=O)N=C2C%10=CC=C(Cl)C=C%10)=NN=C3C)SC1C

Molecular Formula

C79H99ClN16O16S2

Molecular Weight

1628.31

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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