SQA1
Product Specifications
CAS Number
1255915-27-5
Target
CCR, CXCR
Related Pathways
GPCR/G Protein, Microbiology/Virology, Autophagy, Immunology/Inflammation
Bioactivity
SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.
Smiles
N(C1=C(N[C@H](CC)C2=CC(C(C)C)=CO2)C(=O)C1=O)C=3C(O)=C(C(N(C)C)=O)N=CC3
Molecular Formula
C22H26N4O5
Molecular Weight
426.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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