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RMC-113

Product Specifications

CAS Number

2258606-34-5

Target

DNA/RNA Synthesis|||PI3K|||SARS-CoV|||Autophagy

Related Pathways

Cell Cycle/Checkpoint|||Microbiology/Virology|||PI3K/Akt/mTOR signaling|||Autophagy|||DNA Damage/DNA Repair

Bioactivity

RMC-113 is an inhibitor of PIP4K2C and PIKfyve, with Ki values of 46 nM and 370 nM, respectively. It reverses autophagy flux impairment induced by SARS-CoV-2 and exhibits antiviral activity.

Smiles

C(#CC=1SN=C2C=C(C=NC12)C=3C=CC(OC)=C(OC)C3)C=4C=NC=CC4

Molecular Formula

C21H15N3O2S

Molecular Weight

373.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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