PT-88
Product Specifications
CAS Number
2803307-04-0
Target
MTOR
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
PT-88, a highly selective mTOR (Mammalian target of rapamycin) inhibitor (IC 50 =1.2 nM), effectively targets both mTORC1 and mTORC2 complexes. These complexes represent the active isoforms of mTOR protein kinases, integral to cell growth, proliferation, and survival. The utility of PT-88 extends to researching mTOR's involvement in tumorigenesis and development, with significant applications in breast cancer treatments.
Smiles
O=C1OCC2=CC(=CC=C12)NC(=O)NC=3C=CC(=CC3)C=4N=C(N=C(N4)N5C6COCC5CC6)N7C8COCC7CC8
Molecular Formula
C30H31N7O5
Molecular Weight
569.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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