PROTAC VHL-type degrader-1
Product Specifications
CAS Number
2821804-13-9
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTACVHL-type degrader-1 is a VHL-type PROTAC degrader. It promotes the degradation of ATM and synergistically enhances the efficacy of the ATR inhibitor, AZD6738.
Smiles
O=C1\C(\C=2C(N1CCCC3=CN(CCCCCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)N=N3)=CC=CC2)=C\7/C=8C(NC7=O)=CC=CC8
Molecular Formula
C49H55N9O6S
Molecular Weight
898.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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