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PROTAC VHL-type degrader-1

Product Specifications

CAS Number

2821804-13-9

Target

PROTACs

Related Pathways

PROTAC

Bioactivity

PROTACVHL-type degrader-1 is a VHL-type PROTAC degrader. It promotes the degradation of ATM and synergistically enhances the efficacy of the ATR inhibitor, AZD6738.

Smiles

O=C1\C(\C=2C(N1CCCC3=CN(CCCCCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)N=N3)=CC=CC2)=C\7/C=8C(NC7=O)=CC=CC8

Molecular Formula

C49H55N9O6S

Molecular Weight

898.08

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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