EB-PSMA-617

Product Specifications

CAS Number

2250333-97-0

Target

PSMA|||Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related|||Immunology/Inflammation

Bioactivity

EB-PSMA-617 is an advanced version of PSMA-617, designed to enhance pharmacokinetic properties through conjugation with Evans Blue (EB), thereby extending its circulation half-life for improved prostate tumor targeting and radiotherapy effectiveness. In preclinical studies with PC3-PIP-loaded mice, EB-PSMA-617 showed an extended blood half-life, greater accumulation in PSMA-positive tumors, and effective tumor elimination with reduced radioactivity.

Smiles

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