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GNE7599

Product Specifications

Target

Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

GNE7599 is a high-affinity, orally active von Hippel-Lindau (VHL) ligand with a dissociation constant (Kd) of 540 pM. It can be linked via a linker to a protein ligand for the synthesis of PROTAC.

Smiles

[C@@H](C(=O)N1[C@H](C(N[C@@H]2C=3C(=CC(=CC3)C4=C(C)N=CS4)CCCC2)=O)C[C@@H](O)C1)([C@](C)(C)C)N5C=C(N=N5)C6CC6

Molecular Formula

C31H40N6O3S

Molecular Weight

576.75

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/217697283339190278/T88028

CAS Number

2771069-76-0

Available Sizes

Curated Selection

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