GNE7599
Product Specifications
CAS Number
2771069-76-0
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
GNE7599 is a high-affinity, orally active von Hippel-Lindau (VHL) ligand with a dissociation constant (Kd) of 540 pM. It can be linked via a linker to a protein ligand for the synthesis of PROTAC.
Smiles
[C@@H](C(=O)N1[C@H](C(N[C@@H]2C=3C(=CC(=CC3)C4=C(C)N=CS4)CCCC2)=O)C[C@@H](O)C1)([C@](C)(C)C)N5C=C(N=N5)C6CC6
Molecular Formula
C31H40N6O3S
Molecular Weight
576.75
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1380703-01 0.02 mg (E-Coli)
Recombinant Dehalococcoides sp. N utilization substance protein B homolog (nusB)
Ask
View Details 
MBS1380703-02 0.1 mg (E-Coli)
Recombinant Dehalococcoides sp. N utilization substance protein B homolog (nusB)
Ask
View Details MBS1380703-03 0.02 mg (Yeast)
Recombinant Dehalococcoides sp. N utilization substance protein B homolog (nusB)
Ask
View Details 
MBS1380703-04 0.1 mg (Yeast)
Recombinant Dehalococcoides sp. N utilization substance protein B homolog (nusB)
Ask
View Details MBS1380703-05 0.02 mg (Baculovirus)
Recombinant Dehalococcoides sp. N utilization substance protein B homolog (nusB)
Ask
View Details 
MBS1380703-06 0.02 mg (Mammalian-Cell)
Recombinant Dehalococcoides sp. N utilization substance protein B homolog (nusB)
Ask
View Details