TF-S14
Product Specifications
CAS Number
2425563-60-4
Target
ROR
Related Pathways
Metabolism
Bioactivity
TF-S14 is an inverse agonist of RORγt. It functions by binding to RORγt and inhibiting its activity, leading to a reduction in Th17 cell-associated cytokine production, including IL-17A, IL-21, and IL-22. TF-S14 is applicable in research related to autoimmune diseases and allogeneic transplant rejection.
Smiles
C(=O)(C=1C2=C(SC1NC(=O)C=3C=CC=NC3)CCCC2)N4[C@H](C)C[C@H](C)CC4
Molecular Formula
C22H27N3O2S
Molecular Weight
397.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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