ELOVL6-IN-5
Product Specifications
CAS Number
1135000-36-0
Bioactivity
ELOVL6-IN-5 (compound B) acts as an inhibitor targeting the elongase enzyme of the long-chain fatty acid family 6 (ELOVL6) . This enzyme is pivotal in the elongation process of saturated and monounsaturated long-chain fatty acids, marking it as a strategic target for diabetes intervention. In a mouse model of diet-induced obesity (DIO), ELOVL6-IN-5 effectively reduces hepatic fatty acid levels. However, it fails to enhance insulin sensitivity.
Smiles
O=C(NC1=CC=C(C=C1)C(F)(F)F)N2C3CCC2CC(C3)S(=O)(=O)C4=NC=CC=C4
Molecular Formula
C20H20F3N3O3S
Molecular Weight
439.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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