ARN25062
Product Specifications
CAS Number
3036492-85-7
Target
Ras
Related Pathways
MAPK
Bioactivity
ARN25062 is an inhibitor of the protein-protein interaction between Cdc42 and p21-activated kinase (PAK) . It inhibits the proliferation of SKM28, SK-MEL-3, WM3248, and A375 melanoma cells (IC50s = 6.1, 4.6, 9.3, and 5.1 μM, respectively) and SW480 colon cancer cells (IC50 = 5.9 μM) .
Smiles
FC(F)(F)C=1C=CC=C(C1)NC=2N=C(N=C(C2)C=3C=CC=CC3)C4CCNCC4
Molecular Formula
C22H21F3N4
Molecular Weight
398.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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